Glutamate transporters in kidney and brain

被引:46
作者
Hediger, MA
机构
[1] Harvard Univ, Brigham & Womens Hosp, Sch Med, Div Renal, Boston, MA 02115 USA
[2] Harvard Univ, Brigham & Womens Hosp, Sch Med, Membrane & Biol Program, Boston, MA 02115 USA
关键词
sodium-dependent transporters; intracellular pH; cell volume regulation; metabolic acidosis;
D O I
10.1152/ajprenal.1999.277.4.F487
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Glutamate transporters play important roles in the termination of excitatory neurotransmission and in providing cells with glutamate for metabolic purposes. In the kidney, glutamate transporters are involved in reabsorption of filtered acidic amino acids, regulation of ammonia and bicarbonate production, and protection of cells against osmotic stress.
引用
收藏
页码:F487 / F492
页数:6
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