Efficient method for the synthesis of substituted TosMIC precursors

被引：54

作者：

Sisko, J ^{[1
]}

Mellinger, M ^{[1
]}

Sheldrake, PW ^{[1
]}

Baine, NH ^{[1
]}

机构：

[1] SMITHKLINE BEECHAM PHARMACEUT,DEPT SYNTHET CHEM,TONBRIDGE TN11 9AN,ENGLAND

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 45期

关键词：

D O I：

10.1016/0040-4039(96)01886-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Substituted tosylmethyl isocyanides (TosMICs) are useful reagents for which no general method of preparation is available. We describe here a high-yielding method for the synthesis of substituted tosylmethyl formamides, which are readily converted to the corresponding isocyanides. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：8113 / 8116

页数：4

共 15 条

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