Stem cell therapy and gene transfer for regeneration

被引：144

作者：

Asahara, T ^{[1
]}

Kalka, C ^{[1
]}

Isner, JM ^{[1
]}

机构：

[1] Tufts Univ, Sch Med, St Elizabeths Med Ctr, Boston, MA 02135 USA

来源：

GENE THERAPY | 2000年 / 7卷 / 06期

关键词：

stem cell; gene therapy; regeneration; progenitor cell; differentiation;

D O I：

10.1038/sj.gt.3301142

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The committed stem and progenitor cells have been recently isolated from various adult tissues, including hematopoietic stem cell, neural stem cell, mesenchymal stem cell and endothelial progenitor cell. These adult stem cells have several advantages as compared with embryonic stem cells as their practical therapeutic application for tissue regeneration. In this review, we discuss the promising gene therapy application of adult stem and progenitor cells in terms of modifying stem cell potency, altering organ property, accelerating regeneration and forming expressional organization.

引用

页码：451 / 457

页数：7

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