An integrated view of the regulation of NKG2D ligands

被引：66

作者：

Stern-Ginossar, Noam ^{[1
]}

Mandelboim, Ofer ^{[1
]}

机构：

[1] Hebrew Univ Jerusalem, Hadassah Med Sch, Lautenberg Ctr Gen & Tumor Immunol, Biomed Res Inst, IL-91120 Jerusalem, Israel

来源：

IMMUNOLOGY | 2009年 / 128卷 / 01期

关键词：

innate immunity; microRNAs; natural killer cells; NKG2D; stress; NATURAL-KILLER-CELLS; DELTA T-CELLS; HUMAN CYTOMEGALOVIRUS; DENDRITIC CELLS; DOWN-REGULATION; MESSENGER-RNAS; NK CELLS; EXPRESSION; MICRORNAS; RECEPTOR;

D O I：

10.1111/j.1365-2567.2009.03147.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

P>NKG2D is one of the best characterized activating receptors and is expressed on natural killer cells and on various T-cell subsets. This receptor recognizes several different ligands that are induced by cellular stresses. In this review, we described the mechanisms controlling the expression of NKG2D ligands, with the emphasis on post-transcriptional and post-translational regulation.

引用

页码：1 / 6

页数：6

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