Highly active chiral ruthenium catalysts for asymmetric cross- and ring-opening cross metathesis

被引：117

作者：

Berlin, Jacob M. ^{[1
]}

Goldberg, Steven D. ^{[1
]}

Grubbs, Robert H. ^{[1
]}

机构：

[1] CALTECH, Arnold & Mabel Beckman Labs Chem Synth, Div Chem & Chem Engn, Pasadena, CA 91125 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 45期

关键词：

asymmetric catalysis; carbenes; metathesis; reaction mechanisms; ruthenium;

D O I：

10.1002/anie.200602469

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Metathesis takes sides: The scope of asymmetric metathesis has been expanded with the use of chiral ruthenium catalysts for asymmetric ring-opening cross-metathesis and for the first example of an asymmetric cross-metathesis (see scheme, TIPS = triisopropylsilyl). Information about the mechanism of asymmetric ring-opening cross-metathesis should allow the development of more selective catalysts. (Chemical Equation Presented) © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：7591 / 7595

页数：5

共 33 条

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