Immunohistochemical study on the distribution of TRPC channels in the rat hippocampus

被引：59

作者：

Chung, Yoon Hee

Ahn, Hyang Sun

Kim, Daejin

Shin, Dong Hoon

Kim, Sung Su

Kim, Kyung Yong

Lee, Won Bok

Cha, Choong Ik

机构：

[1] Chung Ang Univ, Coll Med, Dept Anat, Seoul 156756, South Korea

[2] Seoul Natl Univ, Coll Med, Dept Anat, Seoul 110799, South Korea

来源：

BRAIN RESEARCH | 2006年 / 1085卷

基金：

新加坡国家研究基金会;

关键词：

transient receptor potential (TRP); channel; TRPC; rat; hippocampus; immunohistochemistry;

D O I：

10.1016/j.brainres.2006.02.087

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In the present study, we performed immunohistochemistry using antibodies directed against TRPCs to study the localizations of these channels in rat hippocampus. The pyramidal cell bodies of CA1-3 areas and the granule cell bodies of the dentate gyrus were immunoreactive for TRPC1, TRPC3, TRPC4 and TRPC5. On the other hand, TRPC6 exhibited the cloud-like neuropil staining only in the molecular layer of the dentate gyrus. As a whole, the present study has clearly shown the localization of TRPCs in rat hippocampus and may provide useful data for the future investigations on the structural and functional properties of TRPCs. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：132 / 137

页数：6

共 20 条

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