Caveats for the Use of Operational Electronic Health Record Data in Comparative Effectiveness Research

被引：354

作者：

Hersh, William R. ^{[1
]}

Weiner, Mark G. ^{[2
]}

Embi, Peter J. ^{[3
]}

Logan, Judith R. ^{[1
]}

Payne, Philip R. O. ^{[3
]}

Bernstam, Elmer V. ^{[4
]}

Lehmann, Harold P. ^{[5
]}

Hripcsak, George ^{[6
]}

Hartzog, Timothy H. ^{[7
]}

Cimino, James J. ^{[8
]}

Saltz, Joel H. ^{[9
]}

机构：

[1] Oregon Hlth & Sci Univ, Dept Med Informat & Clin Epidemiol, Portland, OR 97239 USA

[2] AstraZeneca, Wilmington, DE USA

[3] Ohio State Univ, Wexner Med Ctr, Columbus, OH 43210 USA

[4] Univ Texas Hlth Sci Ctr Houston, Houston, TX 77030 USA

[5] Johns Hopkins Univ, Div Hlth Sci Informat, Baltimore, MD USA

[6] Columbia Univ, Dept Biomed Informat, New York, NY USA

[7] Med Univ S Carolina, Dept Pediat, Charleston, SC 29425 USA

[8] NIH, Ctr Clin, Bethesda, MD 20892 USA

[9] Emory Univ, Ctr Comprehens Informat, Atlanta, GA 30322 USA

来源：

MEDICAL CARE | 2013年 / 51卷 / 08期

基金：

美国国家科学基金会;

关键词：

comparative effectiveness research; electronic health records; clinical data; coded (claims) data; biomedical informatics; MEDICAL-RECORDS; CLINICAL-DATA; SECONDARY USE; CARE DATA; QUALITY; OUTCOMES; IDENTIFICATION; VALIDATION; ASSOCIATION; DIAGNOSES;

D O I：

10.1097/MLR.0b013e31829b1dbd

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

100404 [儿少卫生与妇幼保健学];

摘要：

The growing amount of data in operational electronic health record systems provides unprecedented opportunity for its reuse for many tasks, including comparative effectiveness research. However, there are many caveats to the use of such data. Electronic health record data from clinical settings may be inaccurate, incomplete, transformed in ways that undermine their meaning, unrecoverable for research, of unknown provenance, of insufficient granularity, and incompatible with research protocols. However, the quantity and real-world nature of these data provide impetus for their use, and we develop a list of caveats to inform would-be users of such data as well as provide an informatics roadmap that aims to insure this opportunity to augment comparative effectiveness research can be best leveraged.

引用

页码：S30 / S37

页数：8

共 71 条

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