Therapeutic strategies for allergic diseases

被引：186

作者：

Barnes, PJ ^{[1
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Natl Heart & Lung Inst, Dept Thorac Med, London SW3 6LY, England

来源：

NATURE | 1999年 / 402卷 / 6760期

关键词：

D O I：

10.1038/35037026

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Many drugs are now in development for the treatment of atopic diseases, including asthma, allergic rhinitis and atopic dermatitis. These treatments are based on improvements in existing therapies or on a better understanding of the cellular and molecular mechanisms involved in atopic diseases. Although most attention has been focused on asthma, treatments that inhibit the atonic disease process would have application to all atonic diseases, as they often coincide. Most of the many new therapies in development are aimed at inhibiting components of the allergic inflammatory response, but in the future there are real possibilities for the development of preventative and even curative treatments.

引用

页码：B31 / B38

页数：8

共 99 条

[1] Selectin blockade prevents antigen-induced late bronchial responses and airway hyperresponsiveness in allergic sheep [J].