Visualization for genomics: The microbial genome viewer

被引:51
作者
Kerkhoven, R
van Enckevort, FHJ
Boekhorst, J
Molenaar, D
Siezen, RJ
机构
[1] Univ Nijmegen, Ctr Mol & Biomol Informat, NL-6500 GL Nijmegen, Netherlands
[2] NIZO Food Res, NL-6710 BA Ede, Netherlands
[3] Wageningen Ctr Food Sci, NL-6700 AN Wageningen, Netherlands
关键词
D O I
10.1093/bioinformatics/bth159
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
A Web-based visualization tool, the Microbial Genome Viewer, is presented that allows the user to combine complex genomic data in a highly interactive way. This Web tool enables the interactive generation of chromosome wheels and linear genome maps from genome annotation data stored in a MySQL database. The generated images are in scalable vector graphics (SVG) format, which is suitable for creating high-quality scalable images and dynamic Web representations. Gene-related data such as transcriptome and time-course microarray experiments can be superimposed on the maps for visual inspection.
引用
收藏
页码:1812 / 1814
页数:3
相关论文
共 8 条
[1]  
Bateman A, 2004, NUCLEIC ACIDS RES, V32, pD138, DOI [10.1093/nar/gkp985, 10.1093/nar/gkr1065, 10.1093/nar/gkh121]
[2]   Prediction of transcription terminators in bacterial genomes [J].
Ermolaeva, MD ;
Khalak, HG ;
White, O ;
Smith, HO ;
Salzberg, SL .
JOURNAL OF MOLECULAR BIOLOGY, 2000, 301 (01) :27-33
[3]  
GIBSON G, 2003, BIOINFORMATICS, V19, P1339
[4]   Complete genome sequence of Lactobacillus plantarum WCFS1 [J].
Kleerebezem, M ;
Boekhorst, J ;
van Kranenburg, R ;
Molenaar, D ;
Kuipers, OP ;
Leer, R ;
Tarchini, R ;
Peters, SA ;
Sandbrink, HM ;
Fiers, MWEJ ;
Stiekema, W ;
Lankhorst, RMK ;
Bron, PA ;
Hoffer, SM ;
Groot, MNN ;
Kerkhoven, R ;
de Vries, M ;
Ursing, B ;
de Vos, WM ;
Siezen, RJ .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (04) :1990-1995
[5]   A DNA structural atlas for Escherichia coli [J].
Pedersen, AG ;
Jensen, LJ ;
Brunak, S ;
Stærfeldt, HH ;
Ussery, DW .
JOURNAL OF MOLECULAR BIOLOGY, 2000, 299 (04) :907-930
[6]   GenoMap, a circular genome data viewer [J].
Sato, N ;
Ehira, S .
BIOINFORMATICS, 2003, 19 (12) :1583-1584
[7]   The COG database: new developments in phylogenetic classification of proteins from complete genomes [J].
Tatusov, RL ;
Natale, DA ;
Garkavtsev, IV ;
Tatusova, TA ;
Shankavaram, UT ;
Rao, BS ;
Kiryutin, B ;
Galperin, MY ;
Fedorova, ND ;
Koonin, EV .
NUCLEIC ACIDS RESEARCH, 2001, 29 (01) :22-28
[8]   Combined transcriptome and proteome analysis as a powerful approach to study genes under glucose repression in Bacillus subtilis [J].
Yoshida, K ;
Kobayashi, K ;
Miwa, Y ;
Kang, CM ;
Matsunaga, M ;
Yamaguchi, H ;
Tojo, S ;
Yamamoto, M ;
Nishi, R ;
Ogasawara, N ;
Nakayama, T ;
Fujita, Y .
NUCLEIC ACIDS RESEARCH, 2001, 29 (03) :683-692