A new approach to oligonucleotide labelling using Diels-Alder cycloadditions and detection by SERRS

被引：41

作者：

Fruk, L ^{[1
]}

Grondin, A ^{[1
]}

Smith, WE ^{[1
]}

Graham, D ^{[1
]}

机构：

[1] Univ Strathclyde, Dept Pure & Appl Chem, Glasgow G1 1XL, Lanark, Scotland

来源：

CHEMICAL COMMUNICATIONS | 2002年 / 18期

关键词：

D O I：

10.1039/b204790j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Diels-Alder cycloaddition has been used to add a benzotriazole azo dye to a diene tagged oligonucleotide to generate unique SERRS signals at 10 attomoles.

引用

页码：2100 / 2101

页数：2

共 16 条

[1] Single-molecule detection of specific nucleic acid sequences in unamplified genomic DNA [J].

Castro, A ;

Williams, JGK .

ANALYTICAL CHEMISTRY, 1997, 69 (19) :3915-3920

[2] THIOL-REACTIVE FLUORESCENT-PROBES FOR PROTEIN LABELING [J].

CORRIE, JET .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1994, (20) :2975-2982

[3]

Graham D, 2000, BIOPOLYMERS, V57, P85, DOI 10.1002/(SICI)1097-0282(2000)57:2<85::AID-BIP5>3.0.CO

[4]

2-#

[5] Selective detection of deoxyribonucleic acid at ultralow concentrations by SERRS [J].

Graham, D ;

Smith, WE ;

Linacre, AMT ;

Munro, CH ;

Watson, ND ;

White, PC .

ANALYTICAL CHEMISTRY, 1997, 69 (22) :4703-4707

[6]

Graham D, 2000, ANGEW CHEM INT EDIT, V39, P1061, DOI 10.1002/(SICI)1521-3773(20000317)39:6<1061::AID-ANIE1061>3.0.CO

[7]

2-9

[8] Benzotriazole maleimide as a bifunctional reactant for SERS [J].

Grondin, A ;

Robson, DC ;

Smith, WE ;

Graham, D .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 2001, (11) :2136-2141

[9] SURFACE-ENHANCED RESONANCE RAMAN-SPECTROSCOPY OF RHODAMINE-6G ADSORBED ON COLLOIDAL SILVER [J].

HILDEBRANDT, P ;

STOCKBURGER, M .

JOURNAL OF PHYSICAL CHEMISTRY, 1984, 88 (24) :5935-5944

[10] Diels-Alder bioconjugation of diene-modified oligonucleotides [J].

Hill, KW ;

Taunton-Rigby, J ;

Carter, JD ;

Kropp, E ;

Vagle, K ;

Pieken, W ;

McGee, DPC ;

Husar, GM ;

Leuck, M ;

Anziano, DJ ;

Sebesta, DP .

JOURNAL OF ORGANIC CHEMISTRY, 2001, 66 (16) :5352-5358

← 1 2 →