Plasmodium falciparum AMA1 binds a rhoptry neck protein homologous to TgRON4, a component of the moving junction in Toxoplasma gondii

被引：125

作者：

Alexander, David L.

Arastu-Kapur, Shirin

Dubremetz, Jean-Francois

Boothroyd, John C.

机构：

[1] Stanford Univ, Sch Med, Dept Microbiol & Immunol, Stanford, CA 94305 USA

[2] Stanford Univ, Sch Med, Dept Pathol, Stanford, CA 94305 USA

[3] Univ Montpellier 2, CNRS, UMR 5539, F-34090 Montpellier, France

来源：

EUKARYOTIC CELL | 2006年 / 5卷 / 07期

基金：

英国惠康基金;

关键词：

D O I：

10.1128/EC.00040-06

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Plasmodium falciparum apical membrane antigen I (PfAMA1) coimmunoprecipitates with the Plasmodium homologue of TgRON4, a secreted rhoptry neck protein of Toxoplasma gondii that migrates at the moving junction in association with TgAMA1 during invasion. PfRON4 also originates in the rhoptry necks, suggesting that this unusual collaboration of micronemes and rhoptries is a conserved feature of Apicomplexa.

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页码：1169 / 1173

页数：5

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