Detection of active oxygen generated from ceramic powders having antibacterial activity

被引：274

作者：

Sawai, J ^{[1
]}

Kawada, E ^{[1
]}

Kanou, F ^{[1
]}

Igarashi, H ^{[1
]}

Hashimoto, A ^{[1
]}

Kokugan, T ^{[1
]}

Shimizu, M ^{[1
]}

机构：

[1] TOKYO UNIV AGR & TECHNOL,DEPT CHEM ENGN,DIV APPL CHEM,KOGANEI,TOKYO 184,JAPAN

来源：

JOURNAL OF CHEMICAL ENGINEERING OF JAPAN | 1996年 / 29卷 / 04期

关键词：

biochemical engineering; ceramics; antibacterial activity; active oxygen; chemiluminescence analysis;

D O I：

10.1252/jcej.29.627

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

In order to elucidate the antibacterial mechanisms of magnesium oxide (MgO), calcium oxide (CaO) and zinc oxide (ZnO), the generation of active oxygen from these ceramic powder slurries was examined by oxygen electrode analysis and chemiluminescence analysis. Hydrogen peroxide (H2O2) generated from the ZnO powder slurry was detected using the oxygen electrode. Active oxygen from the MgO and CaO powder slurries was not detected by the oxygen electrode analysis. Chemiluminescence analysis could detect the generation of active oxygen from three kinds of powders. The luminescence response of the CaO powder slurry was markedly strong. The chemiluminescence responses of the CaO and MgO powder slurries are due to the superoxide anion (O-2(-)). The order of the strength of luminescence response was CaO, MgO, and ZnO, which agreed with that of the antibacterial activity of these powders. These results suggested that active oxygen species generated from the ceramic powders were associated with their antibacterial activities.

引用

页码：627 / 633

页数：7

共 36 条

[1] PHAGOCYTIC ACTIVATION OF A LUMINOL-DEPENDENT CHEMILUMINESCENCE IN RABBIT ALVEOLAR AND PERITONEAL MACROPHAGES [J].

ALLEN, RC ;

LOOSE, LD .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1976, 69 (01) :245-252

[2]

ARAI T, 1992, J ANTIBACT ANTIFUNG, V20, P205

[3]

ASADA K, 1987, KASSEI SANSO, P33

[4]

BAHIOR BM, 1973, J CLIN INVEST, V52, P741

[5]

BIARD MJ, 1972, J CATAL, V26, P440

[6] SUPEROXIDE-DISMUTASE ACTIVITY IN THERMALLY STRESSED STAPHYLOCOCCUS-AUREUS [J].

BUCKER, ER ;

MARTIN, SE .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1981, 41 (02) :449-454

[7] HYDROGENATION OF ETHYLENE BY ZINC OXIDE .I. ROLE OF SLOW HYDROGEN CHEMISORPTION [J].

DENT, AL ;

KOKES, RJ .

JOURNAL OF PHYSICAL CHEMISTRY, 1969, 73 (11) :3772-&

[8] OXIDATIVE STRESS RESPONSES IN ESCHERICHIA-COLI AND SALMONELLA-TYPHIMURIUM [J].

FARR, SB ;

KOGOMA, T .

MICROBIOLOGICAL REVIEWS, 1991, 55 (04) :561-585

[9] EFFECT OF AERATION ON MINIMAL MEDIUM RECOVERY OF HEATED SALMONELLA-TYPHIMURIUM [J].

GOMEZ, RF ;

SINSKEY, AJ .

JOURNAL OF BACTERIOLOGY, 1975, 122 (01) :106-109

[10] FREE-RADICAL THEORY OF AGING - THE FREE-RADICAL DISEASES [J].

HARMAN, D .

AGE, 1984, 7 (04) :111-131

← 1 2 3 4 →