Genotyping of hepatitis E virus from Vietnam

被引：17

作者：

Hijikata, M

Hayashi, S

Trinh, NT

Ha, LD

Ohara, H

Shimizu, YK

Keicho, N

Yoshikura, H

机构：

[1] Int Med Ctr Japan, Inst Res, Dept Resp Dis, Shinjuku Ku, Tokyo 1628655, Japan

[2] Int Med Ctr Japan, Dept Gastroenterol, Tokyo 1628655, Japan

[3] Int Med Ctr Japan, Bur Int Cooperat, Tokyo 1628655, Japan

[4] Natl Inst Infect Dis, Tokyo, Japan

[5] Bach Mai Hosp, Inst Clin Res Trop Med, Hanoi, Vietnam

来源：

INTERVIROLOGY | 2002年 / 45卷 / 02期

关键词：

hepatitis E virus; genotype; Vietnam;

D O I：

10.1159/000063231

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

To identify the genotype of Vietnamese isolates of human hepatitis E virus (HEV), phylogenetic analysis was performed for the open reading frame (ORF) 1 and ORF2 nucleotide sequences of the viral genome. HEV was detected by RT-PCR in 9 out of 141 sera collected from patients with a diagnosis of acute sporadic hepatitis in Hanoi, Vietnam. All of them had sequences related most closely to genotype 4. In addition, the Vietnamese isolate had a single nucleotide insertion in the ORF 3 region, a characteristic reported for genotype 4 with the possible change of initiation of ORF 3 and ORF 2. Copyright (C) 2002 S. Karger AG, Basel.

引用

页码：101 / 104

页数：4

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2-4