Modulation of transmitter release at giant synapses of the auditory system

被引：31

作者：

Trussell, LO ^{[1
]}

机构：

[1] Oregon Hlth & Sci Univ, Portland, OR 97201 USA

来源：

CURRENT OPINION IN NEUROBIOLOGY | 2002年 / 12卷 / 04期

关键词：

D O I：

10.1016/S0959-4388(02)00335-5

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The relay nuclei of the auditory brainstem contain some of the largest nerve terminals in the mammalian brain. Endbulb and calyceal synapses convey signals with a high degree of precision and reliability. However, recent studies reveal that these synapses possess numerous and remarkably diverse mechanisms for the modulation of transmitter release. The implication is that successful relay of signals in vivo may require the ability to fine-tune synaptic transmission.

引用

收藏

页码：400 / 404

页数：5

相关论文

共 41 条

[1] PRESYNAPTIC AND POSTSYNAPTIC GLUTAMATE RECEPTORS AT A GIANT EXCITATORY SYNAPSE IN RAT AUDITORY BRAIN-STEM SLICES [J].

BARNESDAVIES, M ;

FORSYTHE, ID .

JOURNAL OF PHYSIOLOGY-LONDON, 1995, 488 (02) :387-406

[2] Pre- and postsynaptic whole-cell recordings in the medial nucleus of the trapezoid body of the rat [J].

Borst, JGG ;

Helmchen, F ;

Sakmann, B .

JOURNAL OF PHYSIOLOGY-LONDON, 1995, 489 (03) :825-840

[3] Enhancement of synaptic efficacy by presynaptic GABAB receptors [J].

Brenowitz, S ;

David, J ;

Trussell, L .

NEURON, 1998, 20 (01) :135-141

[4] Maturation of synaptic transmission at end-bulb synapses of the cochlear nucleus [J].

Brenowitz, S ;

Trussell, LO .

JOURNAL OF NEUROSCIENCE, 2001, 21 (23) :9487-9498

[5] Minimizing synaptic depression by control of release probability [J].

Brenowitz, S ;

Trussell, LO .

JOURNAL OF NEUROSCIENCE, 2001, 21 (06) :1857-1867

[6]

Cajal S. R., 1995, HIST NEUROSCIENCE

[7] Modulation of a presynaptic hyperpolarization-activated cationic current (Ih) at an excitatory synaptic terminal in the rat auditory brainstem [J].

Cuttle, MF ;

Rusznák, Z ;

Wong, AYC ;

Owens, S ;

Forsythe, ID .

JOURNAL OF PHYSIOLOGY-LONDON, 2001, 534 (03) :733-744

[8]

Elezgarai I, 1999, J COMP NEUROL, V411, P431, DOI 10.1002/(SICI)1096-9861(19990830)411:3<431::AID-CNE6>3.0.CO

[9]

2-R

[10] Presynaptic mechanism for phorbol ester-induced synaptic potentiation [J].

Hori, T ;

Takai, Y ;

Takahashi, T .

JOURNAL OF NEUROSCIENCE, 1999, 19 (17) :7262-7267

← 1 2 3 4 5 →