Multi-analyte interrogation using the fiber optic biosensor

被引：83

作者：

Anderson, GP

King, KD

Gaffney, KL

Johnson, LH

机构：

[1] USN, Res Lab, Ctr Biomol Sci & Engn, Washington, DC 20375 USA

[2] Geoctr, Rockville, MD 20852 USA

[3] USN, Med Res Ctr, Biol Def Res Dept, Bethesda, MD 20889 USA

来源：

BIOSENSORS & BIOELECTRONICS | 2000年 / 14卷 / 10-11期

关键词：

fiber optic biosensor; immunoassay;

D O I：

10.1016/S0956-5663(99)00053-6

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

The capabilities of the portable, automated fiber optic biosensor, RAPTOR, have recently been evaluated. Developed to perform rapid fluoroimmunoassays in the field, the RAPTOR was designed to test samples for up to four different target analytes simultaneously. Assay time could be varied from a 3-min rapid screen to a standard 10-min test. A trial of 203 blind samples tested for Staphylococcal enterotoxin B, ricin, Francisella tularensis, and Bacillus globigii has been conducted. Sensitivities obtained were 10, 50 ng/ml, 5 x 10(5), and 5 x 10(4) cfu/ml, respectively. (C) 2000 Elsevier Science S.A. All rights reserved.

引用

页码：771 / 777

页数：7

共 8 条

[1]

BUCHANAN HL, 1997, P US NAVAL I, V123, P83

[2] Why should we be concerned about biological warfare? [J].