Histone deacetylase 1 and 2-controlled embryonic development and cell differentiation

被引：149

作者：

Brunmeir, Reinhard ^{[1
]}

Lagger, Sabine ^{[1
]}

Seiser, Christian ^{[1
]}

机构：

[1] Med Univ Vienna, Vienna Bioctr, Max F Perutz Labs, A-1030 Vienna, Austria

来源：

INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY | 2009年 / 53卷 / 2-3期

关键词：

HDAC1; HDAC2; chromatin; differentiation; development; RESTRICTIVE SILENCER FACTOR; KRUPPEL-LIKE FACTOR; PU.1-MEDIATED TRANSCRIPTIONAL REPRESSION; MEDIATED NEURONAL DIFFERENTIATION; CHROMATIN REMODELING COMPLEXES; DNA METHYLTRANSFERASE 3B; GENE-EXPRESSION; DROSOPHILA-MELANOGASTER; CAENORHABDITIS-ELEGANS; PC12; CELLS;

D O I：

10.1387/ijdb.082649rb

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

During development from the fertilized egg to a multicellular organism, cell fate decisions have to be taken and cell lineage or tissue-specific gene expression patterns are created and maintained. These alterations in gene expression occur in the context of chromatin structure and are controlled by chromatin modifying enzymes. Gene disruption studies in different genetic systems have shown an essential role of various histone deacetylases (HDACs) during early development and cellular differentiation. In this review, we focus on the functions of the class I enzymes HDAC1 and HDAC2 during development in different organisms and summarise the current knowledge about their involvement in neurogenesis, myogenesis, haematopoiesis and epithelial cell differentiation.

引用

收藏

页码：275 / 289

页数：15

相关论文

共 152 条

[1] A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development [J].

Ashe, Alyson ;

Morgan, Daniel K. ;

Whitelaw, Nadia C. ;

Bruxner, Timothy J. ;

Vickaryous, Nicola K. ;

Cox, Liza L. ;

Butterfield, Natalie C. ;

Wicking, Carol ;

Blewitt, Marnie E. ;

Wilkins, Sarah J. ;

Anderson, Gregory J. ;

Cox, Timothy C. ;

Whitelaw, Emma .

GENOME BIOLOGY, 2008, 9 (12)

[2] Control of cardiac growth by histone acetylation/deacetylation [J].

Backs, J ;

Olson, EN .

CIRCULATION RESEARCH, 2006, 98 (01) :15-24

[3] RETRACTED: Identification of T-cadherin as a novel target of DNA methyltransferase 3B and its role in the suppression of nerve growth factor-mediated neurite outgrowth in PC12 cells (Retracted article. See vol. 293, pg. 3592, 2018) [J].

Bai, SM ;

Ghoshal, K ;

Jacob, ST .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (19) :13604-13611

[4] RETRACTED: DNA methyltransferase 3b regulates nerve growth factor-induced differentiation of PC12 cells by recruiting histone deacetylase 2 (Retracted Article) [J].

Bai, SM ;

Ghoshal, K ;

Datta, J ;

Majumder, S ;

Yoon, SO ;

Jacob, ST .

MOLECULAR AND CELLULAR BIOLOGY, 2005, 25 (02) :751-766

[5] Effects of histone deacetylation inhibition on neuronal differentiation of embryonic mouse neural stem cells [J].

Balasubramaniyan, V. ;

Boddeke, E. ;

Bakels, R. ;

Kust, B. ;

Kooistra, S. ;

Veneman, A. ;

Copray, S. .

NEUROSCIENCE, 2006, 143 (04) :939-951

[6] REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis [J].

Ballas, N ;

Grunseich, C ;

Lu, DD ;

Speh, JC ;

Mandel, G .

CELL, 2005, 121 (04) :645-657

[7] The many faces of REST oversee epigenetic programming of neuronal genes [J].

Ballas, N ;

Mandel, G .

CURRENT OPINION IN NEUROBIOLOGY, 2005, 15 (05) :500-506

[8] Regulation of neuronal traits by a novel transcriptional complex [J].

Ballas, N ;

Battaglioli, E ;

Atouf, F ;

Andres, ME ;

Chenoweth, J ;

Anderson, ME ;

Burger, C ;

Moniwa, M ;

Davie, JR ;

Bowers, WJ ;

Federoff, HJ ;

Rose, DW ;

Rosenfeld, MG ;

Brehm, P ;

Mandel, G .

NEURON, 2001, 31 (03) :353-365

[9] FRIEND VIRUS-INDUCED ERYTHROLEUKEMIA AND THE MULTISTAGE NATURE OF CANCER [J].

BENDAVID, Y ;

BERNSTEIN, A .

CELL, 1991, 66 (05) :831-834

[10] β-catenin-histone deacetylase interactions regulate the transition of LEF1 from a transcriptional repressor to an activator [J].

Billin, AN ;

Thirlwell, H ;

Ayer, DE .

MOLECULAR AND CELLULAR BIOLOGY, 2000, 20 (18) :6882-6890

← 1 2 3 4 5 6 7 8 9 10 →