Synthesis of hapalosin and 8-deoxy-hapalosin

被引：35

作者：

Wagner, B ^{[1
]}

Beugelmans, R ^{[1
]}

Zhu, JP ^{[1
]}

机构：

[1] CNRS,INST CHIM SUBST NAT,F-91198 GIF SUR YVETTE,FRANCE

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 36期

关键词：

D O I：

10.1016/0040-4039(96)01415-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Hapalosin, a new MDR reversing agent, and its congener 8-deoxyhapalosin have been synthesized via macrolactamization. A new procedure for selective N-methylation of a vicinal amino alcohol is uncovered in the course of this study. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：6557 / 6560

页数：4

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