Lithium bis-(diisopropylamino)boracetylide [LiC=C-B(Ni-Pr-2)(2)]. A new reagent for the preparation of terminal alkynes

被引：11

作者：

Blanchard, C ^{[1
]}

Vaultier, M ^{[1
]}

Mortier, J ^{[1
]}

机构：

[1] UNIV RENNES 1,CNRS,F-35042 RENNES,FRANCE

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 51期

关键词：

D O I：

10.1016/S0040-4039(97)10394-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Terminal alkynes RC=CH [R = PhCO, PhCH2OCO, (CH3)(2)CHCH2OCO. Et2NCO. (EtO)(2)P(O), PhCH2, H2C=CH-CH2, and Ph-CH(OH)-] may be prepared in satisfactory yield in a one-pot process by reaction in THF at -78 degrees C of the titled reagent with electrophiles followed by acidic workup with dilute HCl. (C) 1997 Elsevier Science Ltd.

引用

页码：8863 / 8866

页数：4

共 13 条

[1]

BACKES J, 1993, HOUBENWEYL METHODEN, V19, P114

[2]

Blanchard C, 1996, SYNTHESIS-STUTTGART, P45

[3]

BLANCHARD C, 1993, Patent No. 4007048

[4] A CONVENIENT SYNTHESIS OF MASKED BETA-KETOALDEHYDES BY THE CONTROLLED ADDITION OF NUCLEOPHILES TO (TRIMETHYLSILYL)ETHYNYL KETONES [J].