False-positive results of enzyme immunoassays for human immunodeficiency virus in patients with uncomplicated malaria

被引:44
作者
Gasasira, Anne F.
Dorsey, Grant
Kamya, Moses R.
Havlir, Diane
Kiggundu, Moses
Rosenthal, Philip J.
Charlebois, Edwin D.
机构
[1] Makerere Univ, Sch Med, Dept Med, Kampala, Uganda
[2] Univ Calif San Francisco, San Francisco Gen Hosp, Dept Med, San Francisco, CA USA
关键词
D O I
10.1128/JCM.02207-05
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Malaria may impact upon human immunodeficiency virus (HIV) test results. We evaluated two HIV enzyme immunoassays (EIAs) by testing 1,965 Ugandans with malaria. We found poor positive predictive values (53% and 76%), particularly with younger age. Combining EIAs eliminated false positives but missed 21% of true positives. Performance of HIV EIAs in malaria may be unsatisfactory.
引用
收藏
页码:3021 / 3024
页数:4
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