2-[2-(hydroxyethyl)phenoxy]benzoic acid

被引:2
作者
Damas, AM
Roleira, FF
Pinto, MMM
机构
[1] UNIV PORTO, INST BIOL MOL & CELULAR, P-4100 OPORTO, PORTUGAL
[2] UNIV PORTO, CTR ESTUDOS QUIM ORGAN FITOQUIM & FARMACOL, P-4100 OPORTO, PORTUGAL
关键词
D O I
10.1107/S0108270197004344
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The three-dimensional structure of the title compound, C15H14O4, has been determined. The molecule assumes a skew conformation, the angle between the two phenyl rings being 84.8(1)degrees. The carboxylic acid substituent is essentially coplanar with the ring. The molecules are connected by O...O intermolecular hydrogen bonds ranging from 2.6 to 2.9 Angstrom. Distorted bond angles at the substituted phenyl C atoms were observed and they agree with the values reported in the literature for other bridged diphenyls.
引用
收藏
页码:1143 / 1145
页数:3
相关论文
共 8 条
[1]  
*CHEM DES LTD, 1993, CHEM X
[2]   CONFORMATIONS OF BRIDGED DIPHENYLS .8. CRYSTAL-STRUCTURE OF 2-(2',6'-DINITROPHENOXY)-TERT-BUTYLBENZENE [J].
GURTU, K ;
CHANDLER, WD ;
ROBERTSON, BE .
CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1975, 53 (14) :2093-2101
[3]   POTENTIAL ANTITUMOR AGENTS .58. SYNTHESIS AND STRUCTURE ACTIVITY RELATIONSHIPS OF SUBSTITUTED XANTHENONE-4-ACETIC ACIDS ACTIVE AGAINST THE COLON 38 TUMOR INVIVO [J].
REWCASTLE, GW ;
ATWELL, GJ ;
BAGULEY, BC ;
CALVELEY, SB ;
DENNY, WA .
JOURNAL OF MEDICINAL CHEMISTRY, 1989, 32 (04) :793-799
[4]   PHASE ANNEALING IN SHELX-90 - DIRECT METHODS FOR LARGER STRUCTURES [J].
SHELDRICK, GM .
ACTA CRYSTALLOGRAPHICA SECTION A, 1990, 46 :467-473
[5]  
SHELDRICK GM, 1993, SHELXL93 PROGRAM REF
[6]  
SZOLNAI L, 1996, XPMA MOL GEOMETRY PR
[7]   CONFORMATIONS OF BRIDGED DIPHENYLS .7. CRYSTAL-STRUCTURE OF 2-(4'-CARBOMETHOXY-2'-NITROPHENOXY)-1,3,5-TRIMETHYLBENZENE [J].
VANDERHEIJDEN, SPN ;
GRIFFITH, EAH ;
CHANDLER, WD ;
ROBERTSON, BE .
CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1975, 53 (14) :2084-2092
[8]  
ZSOLNAI L, 1995, ORTEP PROGRAM SILICO