Application of luminescent nanocrystals as labels for biological molecules

被引：107

作者：

Riegler, J ^{[1
]}

Nann, T ^{[1
]}

机构：

[1] Freiburg Mat Res Ctr FMF, D-79104 Freiburg, Germany

来源：

ANALYTICAL AND BIOANALYTICAL CHEMISTRY | 2004年 / 379卷 / 7-8期

关键词：

quantum dots; luminescent nanocrystals; fluorescence; bioanalysis; fluorescent immunoassays;

D O I：

10.1007/s00216-004-2706-y

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Luminescent semiconductor nanocrystals, so called "quantum dots" (QD), have attracted increasing interest for bioanalytical labeling applications in recent years. This review describes the major optical and (bio)chemical features of this class of label, compared with organic dyes. Different conjugation methods are also discussed and the most important recent applications are presented. An overview over the current state-of-the-art is given, as also is an outlook on possibilities and limitations.

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页码：913 / 919

页数：7

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