Nomograms to help inform women considering Down's syndrome screening

被引:2
作者
Cuckle, HS [1 ]
Sehmi, IK [1 ]
Holding, S [1 ]
机构
[1] ROYAL HULL HOSP,KINGSTON GEN HOSP,DEPT HAEMATOL,KINGSTON HULL HU3 1UR,N HUMBERSIDE,ENGLAND
来源
EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY | 1996年 / 69卷 / 02期
关键词
Down's syndrome; screening; antenatal; biochemical; counselling;
D O I
10.1016/0301-2115(95)02514-6
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To derive graphical information for use in counselling women considering whether or not to have maternal serum screening for Down's syndrome. Design: Statistical modelling of the frequency distribution of estimated Down's syndrome risk for four marker combinations. Results: Nomograms are provided showing for each maternal age: (a) the detection and false-positive rates, and (b) the proportion of pregnancies with different estimated risks. Conclusion: When screening is offered, clinicians need to have information readily available on test accuracy and the likely result, which is specific to the individual.
引用
收藏
页码:69 / 72
页数:4
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