RAP, RAP, open up! New wrinkles for RAP1 in yeast

被引:93
作者
Morse, RH [1 ]
机构
[1] New York State Dept Hlth, Wadsworth Ctr Labs & Res, Mol Genet Program, Albany, NY 12201 USA
[2] SUNY Albany, Sch Publ Hlth, Albany, NY 12201 USA
关键词
D O I
10.1016/S0168-9525(99)01936-8
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
RAP1 (repressor/activator protein 1)from budding yeast is well known far its involvement in gene activation and repression, telomere structure and function, and replication. Recent studies have examined additional roles for RAP1 in heterochromatin boundary-element formation, creation of hotspots for meiotic recombination, and chromatin opening. These studies provide new insight into the ability of this abundant DNA-binding protein to participate in a diverse array of functions taking place in a chromatin environment.
引用
收藏
页码:51 / 53
页数:3
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