Microwave-assisted aminolysis of vinylepoxides

被引：41

作者：

Lindström, UM ^{[1
]}

Olofsson, B

Somfai, P

机构：

[1] Univ Stockholm, Arrhenius Lab, Dept Organ Chem, S-10691 Stockholm, Sweden

[2] Royal Inst Technol, Dept Chem, S-10044 Stockholm, Sweden

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 52期

关键词：

aminoalcohols; aminolysis; microwave heating; ring-opening; vinylepoxides;

D O I：

10.1016/S0040-4039(99)01811-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Di- and trisubstituted vinylepoxides in NH4OH were subjected to microwave irradiation affording the corresponding vicinal aminoalcohols in high yields. The reaction is stereospecific and highly regioselective for addition at the allylic carbon. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：9273 / 9276

页数：4

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