Isolated and Reversible Lesions of the Corpus Callosum: A Distinct Entity

被引：16

作者：

Carlos Garcia-Monco, Juan ^{[1
]}

Martinez, Amaia ^{[1
]}

Pinedo Brochado, Ana ^{[1
]}

Saralegui, Ibone ^{[2
]}

Cabrera, Alberto ^{[2
]}

Gomez Beldarrain, Marian ^{[1
]}

机构：

[1] Hosp Galdakao Usansolo, Serv Neurol, Vizcaya, Spain

[2] Hosp Galdakao Usansolo, Magnet Resonance Unit, Vizcaya, Spain

来源：

JOURNAL OF NEUROIMAGING | 2010年 / 20卷 / 01期

关键词：

Encephalopathy; splenium; reversible lesions; corpus callosum; antiepileptic drugs; seizures; encephalitis; magnetic resonance imaging (MRI);

D O I：

10.1111/j.1552-6569.2009.00427.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The Reversible Splenial Lesion Syndrome represents a distinct clinicoradiological syndrome, associated with several disorders, including infection, high altitude cerebral edema, antiepileptic drug withdrawal, and severe metabolic disturbances (hypoglycemia and hypernatremia). Clinical presentation is nonspecific, most frequently as an encephalopathy or encephalitis. Outcome is favorable in most patients unless there is a severe underlying disorder. Magnetic resonance imaging findings are restricted to the splenium and consist of a nonenhancing oval lesion, hyperintense on T2-weighted images, including FLAIR. Findings on diffusion-weighted imaging are consistent with cytotoxic edema except for high-altitude cerebral edema, where vasogenic edema is present. Resolution after weeks or months is the rule.

引用

页码：1 / 2

页数：2