MULTIPLE SCLEROSIS MRI-the perfect surrogate marker for multiple sclerosis?

被引：24

作者：

Barkhof, Frederik ^{[1
,2
]}

Filippi, Massimo ^{[3
,4
]}

机构：

[1] Vrije Univ Amsterdam, Med Ctr, Dept Radiol, NL-1007 MB Amsterdam, Netherlands

[2] Vrije Univ Amsterdam, Med Ctr, MS Ctr Amsterdam, NL-1007 MB Amsterdam, Netherlands

[3] Inst Sci, Neuroimaging Res Unit, Inst Expt Neurol, Milan, Italy

[4] Univ Hosp San Raffaele, Milan, Italy

来源：

NATURE REVIEWS NEUROLOGY | 2009年 / 5卷 / 04期

关键词：

FOLLOW-UP; MS; DISABILITY; BRAIN;

D O I：

10.1038/nrneurol.2009.31

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

MRI provides a very sensitive reflection of the histopathological changes in multiple sclerosis. Many short-term studies fail to appreciate the relationship between MRI and clinical findings, although such shortcomings might be argued to reflect a weakness of clinical measures, rather than of MRI.

引用

页码：182 / 183

页数：3

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