Peroxisomal β-oxidation enzymes

被引：28

作者：

Hashimoto, T ^{[1
]}

机构：

[1] Shinshu Univ, Sch Med, Dept Biochem, Matsumoto, Nagano 390, Japan

来源：

CELL BIOCHEMISTRY AND BIOPHYSICS | 2000年 / 32卷 / 1-3期

关键词：

bile acid; enzymes; fatty acids; mitochondria; peroxisomes; beta-oxidation;

D O I：

10.1385/CBB:32:1-3:63

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Peroxisomal fatty acid oxidation enzymes are summarized in comparison to their mitochondrial counterparts. The peroxisomal enzymes involved in the beta-oxidation spiral are schematically classified into two groups. The first group consists of hitherto purified and characterized classical enzymes: palmitoyl-CoA oxidase, the L-bifunctional protein, and 3-ketoacyl-CoA. These enzymes are inducible and act on the straight chain substrates. The second group consists of recently identified enzymes, branched-chain oxidase, the D-bifunctional protein, and sterol-carrier protein x, which catalyze four reactions of beta-oxidation cycle. These are noninducible and act on branched-chain substrates.

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页码：63 / 72

页数：10

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