Impact of body mass index on outcome after percutaneous coronary intervention (the obesity paradox)

被引:153
作者
Gurm, HS
Brennan, DM
Booth, J
Tcheng, JE
Lincoff, AM
Topol, EJ
机构
[1] Cleveland Clin Fdn, Dept Cardiovasc Med, Cleveland, OH 44195 USA
[2] Duke Univ, Clin Res Inst, Durham, NC USA
关键词
D O I
10.1016/S0002-9149(02)02384-6
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The impact of body mass index on outcome of patients undergoing percutaneous coronary intervention was assessed in 11,300 patients enrolled in the Evaluation of 7E3 for the Prevention of Ischemic Complications (EPIC), Evaluation of PTCA to Improve Long-term Outcome by cF7E3 Glycoprotein receptor blockade (EPILOG), Integrilin to Minimise Platelet Aggregation and Coronary Thrombosis-II (IMPACT 11). and Evaluation of Platelet IIb/IIIa Inhibitor for Stenting (EPISTENT) trials. Obesity was associated with a significantly reduced risk of myocardial infarction. death, need for urgent revascularization, and major or minor bleeding after percutuneous coronary intervention.
引用
收藏
页码:42 / +
页数:5
相关论文
共 9 条
  • [1] USE OF A MONOCLONAL-ANTIBODY DIRECTED AGAINST THE PLATELET GLYCOPROTEIN IIB/IIIA RECEPTOR IN HIGH-RISK CORONARY ANGIOPLASTY
    CALIFF, RM
    SHADOFF, N
    VALETT, N
    BATES, E
    GALEANA, A
    KNOPF, W
    SHAFTEL, J
    BENDER, MJ
    AVERSANO, T
    RAQUENO, J
    GURBEL, P
    COWFER, J
    COHEN, M
    CROSS, P
    BITTL, J
    EDDINGS, K
    TAYLOR, M
    DEROSA, K
    HATTEL, L
    COOPER, L
    ESHELMAN, B
    FINTEL, D
    NIEMYSKI, P
    KLEIN, L
    KENNEDY, H
    THORNTON, T
    KEREIAKES, D
    MARTIN, L
    ANDERSON, L
    HIGBY, N
    ELLIS, S
    BREZINA, K
    GEORGE, B
    CHAPEKIS, A
    SMITH, D
    ANWAR, A
    GERBER, TL
    PRITCHARD, GL
    MYLER, R
    SHAW, R
    MURPHY, M
    WARD, K
    MADIGAN, NP
    BLANKENSHIP, J
    HALBERT, M
    FLANAGAN, C
    TANNENBAUM, M
    POLICH, M
    STEVENSON, C
    TCHENG, J
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1994, 330 (14) : 956 - 961
  • [2] Body-mass index and mortality in a prospective cohort of US adults
    Calle, EE
    Thun, MJ
    Petrelli, JM
    Rodriguez, C
    Heath, CW
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1999, 341 (15) : 1097 - 1105
  • [3] Low-normal or excessive body mass index: Newly identified and powerful risk factors for death and other complications with percutaneous coronary intervention
    Ellis, SG
    Elliott, J
    Horrigan, M
    Raymond, RE
    Howell, G
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 1996, 78 (06) : 642 - 646
  • [4] The impact of body mass index on short- and long-term outcomes in patients undergoing coronary revascularization - Insights from the Bypass Angioplasty Revascularization Investigation (BAPI)
    Gurm, HS
    Whitlow, PL
    Kip, KE
    BARI Invest
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2002, 39 (05) : 834 - 840
  • [5] IDENTIFICATION AND PRELIMINARY VALIDATION OF PREDICTORS OF MAJOR BLEEDING IN HOSPITALIZED-PATIENTS STARTING ANTICOAGULANT-THERAPY
    LANDEFELD, CS
    COOK, EF
    FLATLEY, M
    WEISBERG, M
    GOLDMAN, L
    [J]. AMERICAN JOURNAL OF MEDICINE, 1987, 82 (04) : 703 - 713
  • [6] RAO AK, 1988, J AM COLL CARDIOL, V11, P1
  • [7] Tcheng JE, 1997, LANCET, V349, P1422
  • [8] Randomised placebo-controlled and balloon-angioplasty-controlled trial to assess safety of coronary stenting with use of platelet glycoprotein-IIb/IIIa blockade
    Topol, EJ
    Lincoff, AM
    Califf, RM
    Tcheng, JE
    Kleiman, NS
    Adelman, AG
    Burton, JR
    Talley, JD
    Ivanhoe, RJ
    Ducas, C
    Cheung, PK
    Schick, U
    Badard, D
    Kramer, J
    Leary, J
    Snyder, H
    Wilson, R
    Dearen, M
    Caramori, P
    Webber, S
    Taylor, J
    Ferrando, T
    Cohen, E
    Balleza, L
    Rouse, C
    Hogg, N
    Kelly, T
    Alston, S
    Webb, J
    Buller, E
    Ricci, DR
    Mockman, S
    Tanguay, JF
    Poitras, AM
    Timis, G
    Davey, D
    Coleman, P
    Herrold-Runge, P
    O'Neill, BJ
    Foshey, K
    Fitzgerald, N
    Almond, D
    Kostuk, W
    White, J
    Oskalns, R
    Gottlieb, R
    Koren, P
    Palazzo, D
    Azrin, M
    Barry, MB
    [J]. LANCET, 1998, 352 (9122) : 87 - 92
  • [9] Topol EJ, 1997, NEW ENGL J MED, V336, P1689