Eales disease - An update

被引:126
作者
Biswas, J
Sharma, T
Gopal, L
Madhavan, HN
Sulochana, KN
Ramakrishnan, S
机构
[1] Med Res Fdn, Madras 600006, Tamil Nadu, India
[2] Vis Res Fdn, Madras 600006, Tamil Nadu, India
关键词
antioxidants; Eales disease; human leukocyte antigen; photocoagulation; polymerase chain reaction; retinal neovascularization; retinal vasculitis; tuberculosis; vitrectomy; vitreous hemorrhage;
D O I
10.1016/S0039-6257(02)00288-6
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Eales disease, first described by Henry Eales in 1880, remains an enigma. The disease, observed more commonly in the Indian subcontinent than in the rest of the world, occurs in young healthy adult males, initially presenting as retinal periphlebitis and later as retinal ischemia that may lead to vascular alterations and neovascularization. Recurrent vitreous hemorrhage with or Without retinal detachment is the common sequelae. In recent years, immunological, molecular biological, and biochemical Studies hake indicated the role of human leukocyte antigen, retinal autoimmunity, mycobacterium tuberculosis genome, and free radical mediated damage in the etiopathogenesis of this disease. However, its etiology appears to be multifactorial. The management depends on the stage of the disease and consists of medical treatment with oral corticosteroids in the active inflammatory stage and laser photocoagulation in the advanced retinal ischemia and neovascularization stages. The results of vitreoretinal surgery have been found to be satisfactory in case of vitreous hemorrhage with or without retinal detachment. (C) 2002 by Elsevier Science Inc. All rights reserved.
引用
收藏
页码:197 / 214
页数:18
相关论文
共 194 条
[1]  
ABRAHAM C, 1977, P ALL INDIA OPHTHALM, V33, P223
[2]  
AGARWAL R, 1998, MACULAR INVOLVEMENT, P118
[3]  
ANDREWS BS, 1977, CLIN EXP IMMUNOL, V29, P23
[4]  
Antiguedad A, 1994, Neurologia, V9, P307
[5]  
ARMSTRONG G, 1995, INVEST OPHTH VIS SCI, V36, P455
[6]  
ARNOLD AC, 1984, OPHTHALMOLOGY, V91, P255
[7]  
ASHTON N, 1962, ACTA 19 CONCILIUM OP, V2, P828
[8]  
ATABAY C, 1992, ANN OPHTHALMOL, V24, P267
[9]  
Atmaca L S, 1993, Ocul Immunol Inflamm, V1, P41, DOI 10.3109/09273949309086536
[10]  
Atmaca L S, 1993, Ocul Immunol Inflamm, V1, P49, DOI 10.3109/09273949309086537