An efficient synthesis of diaryl ketones by iron-catalyzed arylation of aroyl cyanides

被引：131

作者：

Duplais, C

Bures, F

Sapountzis, I

Korn, TJ

Cahiez, G

Knochel, P

机构：

[1] Univ Munich, Dept Chem, D-81377 Munich, Germany

[2] UCP, ESCO, CNRS, Lab Synth Org Select & Chim Organomet, F-95092 Cergy Pontoise, France

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 22期

关键词：

acyl cyanides; homogeneous catalysis; iron; ketones; organomagnesium reagents;

D O I：

10.1002/anie.200453696

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An alternative to acyl chlorides: Iron(III)-catalyzed arylation of aroyl and heteroaroyl cyanides with aryl magnesium reagents (see example in scheme) provides an easy and mild approach to polyfunctionalized diaryl ketones in yields up to 98%.

引用

页码：2968 / 2970

页数：3

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