A new one-pot three-component condensation reaction for the synthesis of 2,3,4,6-tetrasubstituted pyridines

被引：154

作者：

Bagley, MC

Dale, JW

Bower, J

机构：

[1] Cardiff Univ, Dept Chem, Cardiff CF10 3TB, S Glam, Wales

[2] Ribotargets ltd, Cambridge CB1 6GB, England

来源：

CHEMICAL COMMUNICATIONS | 2002年 / 16期

关键词：

D O I：

10.1039/b203900a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The one-pot three-component condensation of a beta-ketoester, ammonia and an alkynone in the presence of a Bronsted or Lewis acid or Amberlyst 15 ion exchange resin provided 2,3,6-trisubstituted or 2,3,4,6-tetrasubstituted pyridines directly in good yield and with total regiocontrol.

引用

页码：1682 / 1683

页数：2

共 13 条

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