Break on through to the other side - the Sec translocon

被引：9

作者：

Eichler, J

Duong, F

机构：

[1] Ben Gurion Univ Negev, Dept Life Sci, IL-84105 Beer Sheva, Israel

[2] Univ Paris 11, Unite Transports & Signalisat Cellulaires, F-91405 Orsay, France

[3] Univ British Columbia, Dept Biochem & Mol Biol, Vancouver, BC V6T 1Z3, Canada

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 2004年 / 29卷 / 05期

关键词：

D O I：

10.1016/j.tibs.2004.03.001

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The transfer of newly synthesized polypeptides across the membrane occurs at the translocon. Although the central role of the translocon in protein translocation is understood, much regarding the manner by which these membrane protein complexes function remains to be learned. The recent solution of the crystal structure of a Sec complex, together with other biochemical, biophysical and structural findings, suggests that answers might be forthcoming.

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收藏

页码：221 / 223

页数：3

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