Structural and functional insights into the assembly of type 1 pili from Escherichia coli

被引:55
作者
Capitani, Guido
Eidam, Oliv
Glockshuber, Rudi
Gruetter, Markus G.
机构
[1] Univ Zurich, Inst Biochem, CH-8057 Zurich, Switzerland
[2] ETH Honggerberg, Inst Mol Biol & Biophys, CH-8093 Zurich, Switzerland
关键词
type; 1; pili; uropathogenic Escherichia coli; structural studies; folding;
D O I
10.1016/j.micinf.2006.03.013
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Type I pili are filamentous protein complexes that are anchored to the outer membrane of uropathogenic Escherichia coli and mediate bacterial adhesion to the surface of urinary epithelium cells. We review here the current status of structural and functional studies on the assembly of type I pili. (c) 2006 Elsevier SAS. All rights reserved.
引用
收藏
页码:2284 / 2290
页数:7
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