Selective ratiometric detection of H2O2 in water and in living cells with boronobenzo[b]quinolizinium derivatives

被引：44

作者：

Bortolozzi, Roberta ^{[1
]}

von Gradowski, Sebastian ^{[2
]}

Ihmels, Heiko ^{[2
]}

Schaefer, Katy ^{[2
]}

Viola, Giampietro ^{[1
]}

机构：

[1] Univ Padua, Dipartimento Salute Donna & Bambino, Lab Oncoematol, I-35028 Padua, Italy

[2] Univ Siegen, Dept Biol Chem, D-57068 Siegen, Germany

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 60期

关键词：

HYDROGEN-PEROXIDE; FLUORESCENT-PROBES; TURN-ON; GENERATION; OXIDATION;

D O I：

10.1039/c4cc02283a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Boronobenzo[b]quinolizinium derivatives exhibit several favorable properties for the fluorimetric detection of hydrogen peroxide, namely quantitative transformation to a product whose emission maximum is well separated from the one of the substrate, water solubility, and the ability to operate in living cells.

引用

页码：8242 / 8245

页数：4

共 37 条

[1] Two-Photon Fluorescence Microscopy Imaging of Cellular Oxidative Stress Using Profluorescent Nitroxides [J].

Ahn, Hyo-Yang ;

Fairfull-Smith, Kathryn E. ;

Morrow, Benjamin J. ;

Lussini, Vanessa ;

Kim, Bosung ;

Bondar, Mykhailo V. ;

Bottle, Steven E. ;

Belfield, Kevin D. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012, 134 (10) :4721-4730

[2] A FRET-based approach to ratiometric fluorescence detection of hydrogen peroxide [J].

Albers, Aaron E. ;

Okreglak, Voytek S. ;

Chang, Christopher J. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (30) :9640-9641

[3] Water-soluble, pH-sensitive fluorescent probes on the basis of acridizinium ions [J].

Bergen, Anna ;

Granzhan, Anton ;

Ihmels, Heiko .

PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES, 2008, 7 (04) :405-407

[4] 9-(4-Dimethylaminophenyl)benzo[b]quinolizinium: A Near-Infrared Fluorophore for the Multicolor Analysis of Proteins and Nucleic Acids in Living Cells [J].

Bortolozzi, Roberta ;

Ihmels, Heiko ;

Thomas, Laura ;

Tian, Maoqun ;

Viola, Giampietro .

CHEMISTRY-A EUROPEAN JOURNAL, 2013, 19 (27) :8736-8741

[5] AROMATIC CYCLODEHYDRATION .35. ALKOXYL DERIVATIVES OF THE ACRIDIZINIUM ION [J].

BRADSHER, CK ;

JONES, JH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1957, 79 (22) :6033-6034

[6] AROMATIC CYCLODEHYDRATION [J].

BRADSHER, CK .

CHEMICAL REVIEWS, 1946, 38 (03) :447-499

[7] Communication -: Superoxide in apoptosis -: Mitochondrial generation triggered by cytochrome c loss [J].

Cai, JY ;

Jones, DP .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (19) :11401-11404

[8] Reaction-Based and Single Fluorescent Emitter Decorated Ratiometric Nanoprobe to Detect Hydrogen Peroxide [J].

Chen, Chun-Yen ;

Chen, Chao-Tsen .

CHEMISTRY-A EUROPEAN JOURNAL, 2013, 19 (47) :16050-16057

[9] Readily Accessible Fluorescent Probes for Sensitive Biological Imaging of Hydrogen Peroxide [J].

Daniel, Kevin B. ;

Agrawal, Arpita ;

Manchester, Marianne ;

Cohen, Seth M. .

CHEMBIOCHEM, 2013, 14 (05) :593-598

[10]

Fink Mitchell P, 2002, Curr Opin Crit Care, V8, P6, DOI 10.1097/00075198-200202000-00002

← 1 2 3 4 →