Expression of E-cadherin, alpha- and beta-catenin mRNAs in ovarian endometriosis

被引：23

作者：

Fujimoto, J

Ichigo, S

Hori, M

Tamaya, T

机构：

[1] Dept. of Obstetrics and Gynecology, Gifu University School of Medicine, Gifu City 500

来源：

EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY | 1996年 / 67卷 / 02期

关键词：

E-cadherin; alpha-catenin; beta-catenin; mRNA expression; ovarian endometriosis;

D O I：

10.1016/0301-2115(96)02432-3

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

To establish the mechanism of development of ovarian endometriosis from the biological function of the adherens junction, we have investigated the expression of E-cadherin, alpha- and beta-catenin mRNAs in ovarian endometriosis in comparison with that in normal uterine endometrium. The expression of E-cadherin, alpha- and beta-catenin mRNAs in ovarian endometriosis was not altered during the menstrual cycle. On the other hand, the expression in normal uterine endometrium significantly was increased at the secretory phase, and was significantly higher than that in ovarian endometriosis. In conclusion, the expression of E-cadherin, alpha- and beta-catenin mRNAs for adherens junction in ovarian endometriosis appeared to be decreased after ovulation, which might, at least in part, contribute to detachment as the first step of development of endometriotic cells.

引用

页码：179 / 183

页数：5

共 23 条

[1] THE COMPLETE SEQUENCE OF A FULL LENGTH CDNA FOR HUMAN-LIVER GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE - EVIDENCE FOR MULTIPLE MESSENGER-RNA SPECIES [J].