Spread of an epidemic Pseudomonas aeruginosa strain from a patient with cystic fibrosis (CF) to non-CF relatives

被引:68
作者
McCallum, SJ
Gallagher, MJ
Corkill, JE
Hart, CA
Ledson, MJ
Walshaw, MJ
机构
[1] Ctr Cardiothorac, Regional Adult Cyst Fibrosis Unit, Liverpool L14 3PE, Merseyside, England
[2] Univ Liverpool, Dept Med Microbiol, Liverpool L69 3BX, Merseyside, England
关键词
D O I
10.1136/thorax.57.6.559
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Colonisation with Pseudomonas aeruginosa is common in adults with cystic fibrosis (CF) and there is increasing evidence that transmissible strains may cross colonise patients. However, transmission of these strains by social contact to healthy non-CF individuals has not been described. A case is presented where an adult CF patient colonised by an epidemic P aeruginosa strain infected her parents with subsequent morbidity.
引用
收藏
页码:559 / 560
页数:2
相关论文
共 7 条
[1]   Spread of beta-lactam-resistant Pseudomonas aeruginosa in a cystic fibrosis clinic [J].
Cheng, K ;
Smyth, RL ;
Govan, JRW ;
Doherty, C ;
Winstanley, C ;
Denning, N ;
Heaf, DP ;
vanSaene, H ;
Hart, CA .
LANCET, 1996, 348 (9028) :639-642
[2]   THE CHANGING EPIDEMIOLOGY OF CYSTIC-FIBROSIS [J].
FITZSIMMONS, SC .
JOURNAL OF PEDIATRICS, 1993, 122 (01) :1-9
[3]   GENOME FINGERPRINTING OF PSEUDOMONAS-AERUGINOSA INDICATES COLONIZATION OF CYSTIC-FIBROSIS SIBLINGS WITH CLOSELY RELATED STRAINS [J].
GROTHUES, D ;
KOOPMANN, U ;
VONDERHARDT, H ;
TUMMLER, B .
JOURNAL OF CLINICAL MICROBIOLOGY, 1988, 26 (10) :1973-1977
[4]   Home-use nebulizers: A potential primary source of Burkholderia cepacia and other colistin-resistant, gram-negative bacteria in patients with cystic fibrosis [J].
Hutchinson, GR ;
Parker, S ;
Pryor, JA ;
DuncanSkingle, F ;
Hoffman, PN ;
Hodson, ME ;
Kaufmann, ME ;
Pitt, TL .
JOURNAL OF CLINICAL MICROBIOLOGY, 1996, 34 (03) :584-587
[5]  
McCallum S, 1999, THORAX, V54, pA3
[6]   Superinfection with a transmissible strain of Pseudomonas aeruginosa in adults with cystic fibrosis chronically colonised by P aeruginosa [J].
McCallum, SJ ;
Corkill, J ;
Gallagher, M ;
Ledson, MJ ;
Hart, CA ;
Walshaw, MJ .
LANCET, 2001, 358 (9281) :558-560
[7]   INTERPRETING CHROMOSOMAL DNA RESTRICTION PATTERNS PRODUCED BY PULSED-FIELD GEL-ELECTROPHORESIS - CRITERIA FOR BACTERIAL STRAIN TYPING [J].
TENOVER, FC ;
ARBEIT, RD ;
GOERING, RV ;
MICKELSEN, PA ;
MURRAY, BE ;
PERSING, DH ;
SWAMINATHAN, B .
JOURNAL OF CLINICAL MICROBIOLOGY, 1995, 33 (09) :2233-2239