Eotaxin: from an eosinophilic chemokine to a major regulator of allergic reactions

被引：95

作者：

Gutierrez-Ramos, JC ^{[1
]}

Lloyd, C ^{[1
]}

Gonzalo, JA ^{[1
]}

机构：

[1] Millennium Pharmaceut Inc, Cambridge, MA 02139 USA

来源：

IMMUNOLOGY TODAY | 1999年 / 20卷 / 11期

关键词：

D O I：

10.1016/S0167-5699(99)01522-4

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Eotaxin has a variety of effects on several cell types that are involved in the allergic inflammatory response. Here, lose Carlos Gutierrez-Ramos and colleagues review the chemotactic effects of eotaxin on eosinophils and T helper type 2 cells, ifs differentiation and migration effects on mast cells and its actions an progenitors and mature cells in the bone marrow.

引用

页码：500 / 504

页数：5

共 52 条

[1] The chemokine SDF-1 is a chemoattractant for human CD34(+) hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34(+) progenitors to peripheral blood
Aiuti, A
Webb, IJ
Bleul, C
Springer, T
GutierrezRamos, JC
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1997, 185 (01) : 111 - 120
[2] Eotasin: A VIC (very important chemokine) of allergic inflammation?
Baggiolini, M
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1996, 97 (03) : 587 - 587
[3] CC-CHEMOKINES IN ALLERGIC INFLAMMATION
BAGGIOLINI, M
DAHINDEN, CA
[J]. IMMUNOLOGY TODAY, 1994, 15 (03): : 127 - 133
[4] Human chemokines: An update
Baggiolini, M
Dewald, B
Moser, B
[J]. ANNUAL REVIEW OF IMMUNOLOGY, 1997, 15 : 675 - 705
[5] Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s
Bonecchi, R
Bianchi, G
Bordignon, PP
D'Ambrosio, D
Lang, R
Borsatti, A
Sozzani, S
Allavena, P
Gray, PA
Mantovani, A
Sinigaglia, F
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1998, 187 (01) : 129 - 134
[6] BRADDING P, 1995, J IMMUNOL, V155, P297
[7] EOSINOPHILS, T-LYMPHOCYTES, MAST-CELLS, NEUTROPHILS, AND MACROPHAGES IN BRONCHIAL BIOPSY SPECIMENS FROM ATOPIC SUBJECTS WITH ASTHMA - COMPARISON WITH BIOPSY SPECIMENS FROM ATOPIC SUBJECTS WITHOUT ASTHMA AND NORMAL CONTROL SUBJECTS AND RELATIONSHIP TO BRONCHIAL HYPERRESPONSIVENESS
BRADLEY, BL
AZZAWI, M
JACOBSON, M
ASSOUFI, B
COLLINS, JV
IRANI, AMA
SCHWARTZ, LB
DURHAM, SR
JEFFERY, PK
KAY, AB
[J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1991, 88 (04) : 661 - 674
[8] B-CELL STIMULATORY FACTOR-I INTERLEUKIN-4 MESSENGER-RNA IS EXPRESSED BY NORMAL AND TRANSFORMED MAST-CELLS
BROWN, MA
PIERCE, JH
WATSON, CJ
FALCO, J
IHLE, JN
PAUL, WE
[J]. CELL, 1987, 50 (05) : 809 - 818
[9] MYELOPOIETIC ENHANCING EFFECTS OF MURINE MACROPHAGE INFLAMMATORY PROTEIN-1 AND PROTEIN-2 ON COLONY FORMATION INVITRO BY MURINE AND HUMAN-BONE MARROW GRANULOCYTE MACROPHAGE PROGENITOR CELLS
BROXMEYER, HE
SHERRY, B
LU, L
COOPER, S
CAROW, C
WOLPE, SD
CERAMI, A
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1989, 170 (05) : 1583 - 1594
[10] NEUTROPHIL AND B-CELL EXPANSION IN MICE THAT LACK THE MURINE IL-8 RECEPTOR HOMOLOG
CACALANO, G
LEE, J
KIKLY, K
RYAN, AM
PITTSMEEK, S
HULTGREN, B
WOOD, WI
MOORE, MW
[J]. SCIENCE, 1994, 265 (5172) : 682 - 684

← 1 2 3 4 5 6 →