Glycoproteins gB, gD, and gHgL of herpes simplex virus type 1 are necessary and sufficient to mediate membrane fusion in a Cos cell transfection system
被引:302
作者:
Turner, A
论文数: 0引用数: 0
h-index: 0
机构:
UNIV CAMBRIDGE, DEPT PATHOL, DIV VIROL, CAMBRIDGE CB2 1QP, ENGLANDUNIV CAMBRIDGE, DEPT PATHOL, DIV VIROL, CAMBRIDGE CB2 1QP, ENGLAND
Turner, A
[1
]
Bruun, B
论文数: 0引用数: 0
h-index: 0
机构:
UNIV CAMBRIDGE, DEPT PATHOL, DIV VIROL, CAMBRIDGE CB2 1QP, ENGLANDUNIV CAMBRIDGE, DEPT PATHOL, DIV VIROL, CAMBRIDGE CB2 1QP, ENGLAND
Bruun, B
[1
]
Minson, T
论文数: 0引用数: 0
h-index: 0
机构:
UNIV CAMBRIDGE, DEPT PATHOL, DIV VIROL, CAMBRIDGE CB2 1QP, ENGLANDUNIV CAMBRIDGE, DEPT PATHOL, DIV VIROL, CAMBRIDGE CB2 1QP, ENGLAND
Minson, T
[1
]
Browne, H
论文数: 0引用数: 0
h-index: 0
机构:
UNIV CAMBRIDGE, DEPT PATHOL, DIV VIROL, CAMBRIDGE CB2 1QP, ENGLANDUNIV CAMBRIDGE, DEPT PATHOL, DIV VIROL, CAMBRIDGE CB2 1QP, ENGLAND
Browne, H
[1
]
机构:
[1] UNIV CAMBRIDGE, DEPT PATHOL, DIV VIROL, CAMBRIDGE CB2 1QP, ENGLAND
Herpes simplex virus type 1 glycoproteins gB, gD, and gHgL were expressed by transient transfection of Cos cells. Polykaryocyte formation above the background level seen in untransfected controls was observed only if all three components were expressed. Thus, gB, gD, and gHgL are necessary and sufficient to induce membrane fusion.