Glycoproteins gB, gD, and gHgL of herpes simplex virus type 1 are necessary and sufficient to mediate membrane fusion in a Cos cell transfection system

被引:302
作者
Turner, A [1 ]
Bruun, B [1 ]
Minson, T [1 ]
Browne, H [1 ]
机构
[1] UNIV CAMBRIDGE, DEPT PATHOL, DIV VIROL, CAMBRIDGE CB2 1QP, ENGLAND
基金
英国惠康基金;
关键词
D O I
10.1128/JVI.72.1.873-875.1998
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Herpes simplex virus type 1 glycoproteins gB, gD, and gHgL were expressed by transient transfection of Cos cells. Polykaryocyte formation above the background level seen in untransfected controls was observed only if all three components were expressed. Thus, gB, gD, and gHgL are necessary and sufficient to induce membrane fusion.
引用
收藏
页码:873 / 875
页数:3
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