Symptomatic vertebral hemangiomas: Treatment by means of direct intralesional injection of ethanol

被引:135
作者
Doppman, JL
Oldfield, EH
Heiss, JD
机构
[1] NIH, Warren Grant Magnuson Clin Ctr, Dept Diagnost Radiol, Bethesda, MD 20892 USA
[2] NINDS, Surg Neurol Branch, NIH, Bethesda, MD 20892 USA
关键词
angioma; skeletal system; spinal cord; compression; spine; angiography; interventional procedures;
D O I
10.1148/radiology.214.2.r00fe46341
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
PURPOSE: To describe the technique and results of injecting ethanol directly into symptomatic vertebral hemangiomas. MATERIALS AND METHODS: Eleven patients with paraplegia (n = 6) or radiculopathy (n = 5) due to vertebral hemangioma were treated by means of injecting ethanol (5-50 mt) directly into the lesion with computed tomographic (CT) guidance. CT angiograms were essential prior to treatment to identify functional vascular spaces of the hemangioma and direct needle placement. RESULTS: All hemangiomas were obliterated completely at follow-up angiography and gadolinium-enhanced magnetic resonance imaging. Five of six patients with paraplegia recovered completely: One who was treated recently was walking with assistance. Four of five patients with radiculopathy improved. No immediate complications were associated with ethanol injection. The two patients who received the largest volumes of ethanol, 42 and 50 mt, developed pathologic fractures of the involved vertebrae 4 and 16 weeks after treatment. CONCLUSION: Direct injection of ethanol into symptomatic vertebral hemangioma is an effective and safe treatment, provided the dose is less than 15 mL.
引用
收藏
页码:341 / 348
页数:8
相关论文
共 26 条
[1]  
Cotten A, 1996, AM J NEURORADIOL, V17, P137
[2]  
DERAMOND H, 1989, RACHIS, V1, P143
[3]   MULTIPLE VERTEBRAL HEMANGIOMAS WITH NEUROLOGICAL SIGNS - CASE-REPORT [J].
DJINDJIAN, M ;
NGUYEN, JP ;
GASTON, A ;
PAVLOVITCH, JM ;
POIRIER, J ;
AWAD, IA .
JOURNAL OF NEUROSURGERY, 1992, 76 (06) :1025-1028
[4]  
Dousset V, 1996, NEURORADIOLOGY, V38, P392
[5]   RADIOTHERAPY IN THE TREATMENT OF VERTEBRAL HEMANGIOMAS [J].
FARIA, SL ;
SCHLUPP, WR ;
CHIMINAZZO, H .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1985, 11 (02) :387-390
[6]  
FOX MW, 1993, NEUROSURGERY, V78, P36
[7]  
Galibert P, 1990, Chirurgie, V116, P326
[8]  
GALIBERT P, 1987, NEUROCHIRURGIE, V33, P166
[9]  
GANGI A, 1994, AM J NEURORADIOL, V15, P83
[10]  
GLANZMANN C, 1977, STRAHLENTHER ONKOL, V153, P522