First total synthesis of natural aplyolides C and E, ichthyotoxic macrolides isolated from the skin of the marine mollusc Aplysia depilans

被引：16

作者：

Caruso, T ^{[1
]}

Spinella, A ^{[1
]}

机构：

[1] Univ Salerno, Dipartimento Chim, I-84081 Baronissi, Salerno, Italy

来源：

TETRAHEDRON-ASYMMETRY | 2002年 / 13卷 / 19期

关键词：

D O I：

10.1016/S0957-4166(02)00575-X

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A convergent pathway is described for the synthesis of the marine macrolides aplyolides C 4 and E 5. The key fragment 8 was prepared stereo selectively by Sharpless asymmetric dihydroxylation of eneyne 13. (C) 2002 Elsevier Science Ltd. All rights reserved.

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页码：2071 / 2073

页数：3

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