Chinese herbs and warfarin potentiation by 'Danshen'

被引：96

作者：

Yu, CM ^{[1
]}

Chan, JCN ^{[1
]}

Sanderson, JE ^{[1
]}

机构：

[1] CHINESE UNIV HONG KONG,PRINCE WALES HOSP,DEPT MED,SHATIN,NT,HONG KONG

来源：

JOURNAL OF INTERNAL MEDICINE | 1997年 / 241卷 / 04期

关键词：

warfarin; Chinese; herbs;

D O I：

10.1046/j.1365-2796.1997.134137000.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Drug interactions with warfarin can be dangerous and although common drug interactions are now well recognized those with Chinese herbs are not widely appreciated. 'Danshen' is a herbal medicine often used for various complaints, particularly cardiovascular, in the Chinese community. We report a case of danshen-induced overcoagulation with severe and dangerous abnormalities of clotting in a patient with rheumatic heart disease.

引用

页码：337 / 339

页数：3

共 10 条

[1] Adverse interactions between warfarin and nonsteroidal antiinflammatory drugs: Mechanisms, clinical significance, and avoidance [J].

Chan, TYK .

ANNALS OF PHARMACOTHERAPY, 1995, 29 (12) :1274-1283

[2]

LANDEFELD CS, 1989, AM J MED, V87, P1539

[3] CARDIOVASCULAR PHARMACOLOGY OF PANAX-NOTOGINSENG (BURK) CHEN,F.H. AND SALVIA-MILTIORRHIZA [J].

LEI, XL ;

CHIOU, GCY .

AMERICAN JOURNAL OF CHINESE MEDICINE, 1986, 14 (3-4) :145-152

[4] HYPOTENSIVE ACTION OF SALVIA-MILTIORRHIZA CELL-CULTURE EXTRACT [J].

LI, CP ;

YUNG, KH ;

CHIU, KW .

AMERICAN JOURNAL OF CHINESE MEDICINE, 1990, 18 (3-4) :157-166

[5] THE EFFECTS OF DANSHEN (SALVIA-MILTIORRHIZA) ON PHARMACO-KINETICS AND PHARMACODYNAMICS OF WARFARIN IN RATS [J].

LO, ACT ;

CHAN, K ;

YEUNG, JHK ;

WOO, KS .

EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 1992, 17 (04) :257-262

[6] PROTHROMBIN TIME RATIO AND OTHER FACTORS ASSOCIATED WITH BLEEDING IN PATIENTS TREATED WITH WARFARIN [J].

PETITTI, DB ;

STROM, BL ;

MELMON, KL .

JOURNAL OF CLINICAL EPIDEMIOLOGY, 1989, 42 (08) :759-764

[7] WARFARIN INTERACTIONS WITH CHINESE TRADITIONAL MEDICINES - DANSHEN AND METHYL SALICYLATE MEDICATED OIL [J].

TAM, LS ;

CHAN, TYK ;

LEUNG, WK ;

CRITCHLEY, JAJH .

AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 1995, 25 (03) :258-258

[8]

WANG Z, 1982, THROMB HAEMOSTASIS, V48, P301

[9]

YOKOZAWA T, 1989, JPN J NEPHROL, V31, P1091

[10]

Zhang X, 1994, J Tradit Chin Med, V14, P292

← 1 →