No evidence for decreasing semen quality in four birth cohorts of 1,055 Danish men born between 1950 and 1970

被引:56
作者
Rasmussen, PE
Erb, K
Westergaard, LG
Laursen, SB
机构
[1] Fertility Clinic, Dept. of Obstetrics and Gynaecology, Odense University Hospital, Odense
[2] Fertility Clinic, Odense University Hospital
关键词
male factor infertility; semen quality; sperm concentration; semen volume; time-related change;
D O I
10.1016/S0015-0282(97)00377-4
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To compare the quality of semen in 1,055 Danish men born between 1950 and 1970 who are assumed to represent a random sample of the Danish male population of fertile age. Design: Retrospective review of data on semen quality at the time of the female partner's first IVF treatment. Setting: The Fertility Clinic, Odense University Hospital, Odense, Denmark. Patient(s): One thousand fifty-five male partners of women with tubal infertility who were referred for IVF treatment consecutively during the period 1990-1996. Intervention(s): Analysis of the semen samples delivered and used in connection with the couples' first IVF treatment. Main Outcome Measure(s): Year of birth, age at time of sample collection, sperm concentration, and semen volume. Result(s): The mean sperm concentration (+/-SD) was 183.7 x 10(6) mt and the mean semen volume (+/-SD) was 3.9 mt. A considerable variation in both parameters was found from year to year, but no significant change occurred in either parameter throughout the entire period. When four birth cohorts were compared, a later year of birth was not associated with any change in sperm concentration or semen volume. Conclusion(s): Sperm concentration and semen volume were not related to year of birth, indicating that sperm quality has not changed in the Danish male population during the last 20-30 years. (C) 1997 by American Society for Reproductive Medicine.
引用
收藏
页码:1059 / 1064
页数:6
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