Association of serum apolipoprotein A-II concentration with combined hyperlipidemia and impaired glucose tolerance

被引：3

作者：

Aleksandrovich, O. V. ^{[1
]}

Ozerova, I. N. ^{[1
]}

Olfer'ev, A. M. ^{[1
]}

Serdyuk, A. P. ^{[1
]}

Metel'skaya, V. A. ^{[1
]}

Perova, N. V. ^{[1
]}

机构：

[1] Russian Hlth Serv, State Res Ctr Prevent Med, Dept Metab Disorders, Moscow, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2006年 / 141卷 / 06期

关键词：

apolipoprotein A-II; hyperlipidemia; insulin resistance;

D O I：

10.1007/s10517-006-0250-9

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

We studied the relationship of serum apolipoprotein A-II concentration with biochemical parameters of lipid and carbohydrate metabolism, type of hyperlipidemia, and insulin resistance in male patients with hyperlipidemia. High concentration of apolipoprotein A-II was associated with increased indices of atherogenic lipoproteins and high-density lipoprotein-mediated reverse cholesterol transport, combined hyperlipidemia, and decreased insulin resistance calculated with consideration for glucose and insulin levels in glucose tolerance test and body weight.

引用

页码：678 / 681

页数：4

共 15 条

[1] Biochemical and genetic association of plasma apolipoprotein A-II levels with familial combined hyperlipidemia [J].

Allayee, H ;

Castellani, LW ;

Cantor, RM ;

de Bruin, TWA ;

Lusis, AJ .

CIRCULATION RESEARCH, 2003, 92 (11) :1262-1267

[2]

Blanco-Vaca F, 2001, J LIPID RES, V42, P1727

[3] Apolipoprotein A-II regulates HDL stability and affects hepatic lipase association and activity [J].

Boucher, J ;

Ramsamy, TA ;

Braschi, S ;

Sahoo, D ;

Neville, TAM ;

Sparks, DL .

JOURNAL OF LIPID RESEARCH, 2004, 45 (05) :849-858

[4] Mechanisms mediating insulin resistance in transgenic mice overexpressing mouse apolipoprotein A-II [J].

Castellani, LW ;

Gargalovic, P ;

Febbraio, M ;

Charugundla, S ;

Jien, ML ;

Lusis, AJ .

JOURNAL OF LIPID RESEARCH, 2004, 45 (12) :2377-2387

[5] European guidelines on cardiovascular disease prevention in clinical practice -: Third Joint Task Force of European and other Societies on Cardiovascular Disease Prevention in Clinical Practice [J].

De Backer, G ;

Ambrosioni, E ;

Borch-Johnsen, K ;

Brotons, C ;

Cifkova, R ;

Dallongeville, J ;

Ebrahim, S ;

Faergeman, O ;

Graham, I ;

Mancia, G ;

Cats, VM ;

Orth-Gomér, K ;

Perk, J ;

Pyörälä, K ;

Rodicio, JL ;

Sans, S ;

Sansoy, V ;

Sechtem, U ;

Silber, S ;

Thomsen, T ;

Wood, D .

EUROPEAN HEART JOURNAL, 2003, 24 (17) :1601-1610

[6]

DOLGOV VV, 2002, LAB DIAGNOSTICS DIST

[7] Evaluation of apolipoprotein A-II as a positional candidate gene for familial Type II diabetes, altered lipid concentrations, and insulin resistance [J].

Elbein, SC ;

Chu, W ;

Ren, Q ;

Wang, H ;

Hemphill, C ;

Hasstedt, SJ .

DIABETOLOGIA, 2002, 45 (07) :1026-1033

[8] Analysis of the relationship between triglyceridemia and HDL-phospholipid concentrations: consequences on the efflux capacity of serum in the Fu5AH system [J].

Fournier, N ;

Atger, W ;

Cogny, A ;

Vedie, B ;

Giral, P ;

Simon, A ;

Moatti, N ;

Paul, JL .

ATHEROSCLEROSIS, 2001, 157 (02) :315-323

[9] Validation of the insulin sensitivity index (ISI0,120):: comparison with other measures [J].

Gutt, M ;

Davis, CL ;

Spitzer, SB ;

Llabre, MM ;

Kumar, M ;

Czarnecki, EM ;

Schneiderman, N ;

Skyler, JS ;

Marks, JB .

DIABETES RESEARCH AND CLINICAL PRACTICE, 2000, 47 (03) :177-184

[10] Apolipoprotein A-II: Beyond genetic associations with lipid disorders and insulin resistance [J].

Kalopissis, AD ;

Pastier, D ;

Chambaz, J .

CURRENT OPINION IN LIPIDOLOGY, 2003, 14 (02) :165-172

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