Failure of pre-diarrheal antibiotics to prevent hemolytic uremic syndrome in serologically proven Escherichia coli O157:H7 gastrointestinal infection

被引：17

作者：

Igarashi, T ^{[1
]}

Inatomi, J ^{[1
]}

Wake, A ^{[1
]}

Takamizawa, M ^{[1
]}

Katayama, H ^{[1
]}

Iwata, T ^{[1
]}

机构：

[1] Univ Tokyo, Fac Med, Dept Pediat, Bunkyo Ku, Tokyo 1128688, Japan

来源：

JOURNAL OF PEDIATRICS | 1999年 / 135卷 / 06期

关键词：

D O I：

10.1016/S0022-3476(99)70100-9

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

A girl had hemolytic uremic syndrome after Escherichia coli O157:H7 infection, despite pre-diarrheal administration of an antibiotic that prevented detectable intestinal colonization. This report casts doubt on the advisability of antibiotic therapy for E coli O157:H7 infections and has implications for our understanding of the mechanism of this disorder.

引用

页码：768 / 769

页数：2

共 10 条

[1]

[Anonymous], ESCHERICHIA COLI 015

[2] A SEVERE OUTBREAK OF ESCHERICHIA-COLI O157-H7 - ASSOCIATED HEMORRHAGIC COLITIS IN A NURSING-HOME [J].

CARTER, AO ;

BORCZYK, AA ;

CARLSON, JAK ;

HARVEY, B ;

HOCKIN, JC ;

KARMALI, MA ;

KRISHNAN, C ;

KORN, DA ;

LIOR, H .

NEW ENGLAND JOURNAL OF MEDICINE, 1987, 317 (24) :1496-1500

[3] HUMORAL IMMUNE-RESPONSES TO SHIGA-LIKE TOXINS AND ESCHERICHIA-COLI O157 LIPOPOLYSACCHARIDE IN HEMOLYTIC-UREMIC SYNDROME PATIENTS AND HEALTHY-SUBJECTS [J].

GREATOREX, JS ;

THORNE, GM .

JOURNAL OF CLINICAL MICROBIOLOGY, 1994, 32 (05) :1172-1178

[4]

Higami S, 1998, Kansenshogaku Zasshi, V72, P266

[5]

Kohsaka T, 1997, Nihon Rinsho, V55, P706

[6] EXPERIMENTAL VEROCYTOTOXEMIA IN RABBITS [J].

RICHARDSON, SE ;

ROTMAN, TA ;

JAY, V ;

SMITH, CR ;

BECKER, LE ;

PETRIC, M ;

OLIVIERI, NF ;

KARMALI, MA .

INFECTION AND IMMUNITY, 1992, 60 (10) :4154-4167

[7] A nationwide case-control study of Escherichia coli O157:H7 infection in the United States [J].

Slutsker, L ;

Ries, AA ;

Maloney, K ;

Wells, JG ;

Greene, KD ;

Griffin, PM .

JOURNAL OF INFECTIOUS DISEASES, 1998, 177 (04) :962-966

[8] Verotoxins induce apoptosis in human renal tubular epithelium derived cells [J].

Taguchi, T ;

Uchida, H ;

Kiyokawa, N ;

Mori, T ;

Sato, N ;

Horie, H ;

Takeda, T ;

Fujimoto, J .

KIDNEY INTERNATIONAL, 1998, 53 (06) :1681-1688

[9]

Takeda T, 1998, ESCHERICHIA COLI O15, P385

[10]

Yoh M, 1997, Kansenshogaku Zasshi, V71, P1144

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