BAli-Phy: simultaneous Bayesian inference of alignment and phylogeny

被引：171

作者：

Suchard, Marc A. ^{[1
]}

Redelings, Benjamin D.

机构：

[1] Univ Calif Los Angeles, David Geffen Sch Med, Dept Biomath, Los Angeles, CA 90095 USA

[2] Univ Calif Los Angeles, David Geffen Sch Med, Dept Human Genet, Los Angeles, CA 90095 USA

[3] N Carolina State Univ, Bioinformat Res Ctr, Raleigh, NC 27606 USA

来源：

BIOINFORMATICS | 2006年 / 22卷 / 16期

关键词：

D O I：

10.1093/bioinformatics/btl175

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

BAli-Phy is a Bayesian posterior sampler that employs Markov chain Monte Carlo to explore the joint space of alignment and phylogeny given molecular sequence data. Simultaneous estimation eliminates bias toward inaccurate alignment guide-trees, employs more sophisticated substitution models during alignment and automatically utilizes information in shared insertion/deletions to help infer phylogenies.

引用

页码：2047 / 2048

页数：2

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