Four Novel Resistance Integron Gene-Cassette Occurrences in Bacterial Isolates from Zhenjiang, China

被引：40

作者：

Xu, Huaxi ^{[1
,2
]}

Su, Zhaoliang ^{[2
]}

Wang, Shengjun ^{[2
]}

Dai, Xiaoli ^{[2
]}

Chen, Jianguo ^{[2
]}

Kong, Fanzhi ^{[2
]}

Li, Yazhen ^{[2
]}

Peng, Sufang ^{[2
]}

Shao, Qixiang ^{[2
]}

Lu, Liwei ^{[2
]}

Ezaki, T. ^{[3
]}

机构：

[1] Jiangsu Univ, Sch Med Technol, Jiangsu 212013, Peoples R China

[2] Jiangsu Univ, Inst Clin Lab Med, Dept Microbiol & Immunol, Zhenjiang 212013, Peoples R China

[3] Gifu Univ, Grad Sch Med, Dept Microbiol Regenerat & Adv Med Sci, Gifu, Japan

来源：

CURRENT MICROBIOLOGY | 2009年 / 59卷 / 02期

关键词：

BETA-LACTAMASE GENE; ESCHERICHIA-COLI; ANTIMICROBIAL RESISTANCE; KLEBSIELLA-PNEUMONIAE; CLASS-1; SALMONELLA; ANIMALS; PCR;

D O I：

10.1007/s00284-009-9405-z

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学];

摘要：

Integrons, which are widely distributed among bacteria and are strongly associated with resistance, are specialized genetic elements that are capable of capturing, integrating, and mobilizing gene cassette. In this work, we investigated classes 1, 2, and 3 integrons associated integrases genes in 365 bacteria isolates, amplified and analyzed the structure of class 1 integron, detected 8 resistant gene cassettes [dfr17, aadA5, aadA1, aadA2, dhfrI, aadB, aac(6')-II, and pse-I], and found four novel gene-cassette arrays. We also found that commensal bacteria in the common microenvironment had the same integron gene cassette, which provided direct evidence that integron was an important horizontal transmission element.

引用

页码：113 / 117

页数：5

共 21 条

[1]

Molecular characterization of a new class 3 integron in Klebsiella pneumoniae [J].