Human breast cancer specimens: Diffraction-enhance imaging with histologic correlation - Improved conspicuity of lesion detail compared with digital radiography

被引：172

作者：

Pisano, ED

Johnston, RE

Chapman, D

Geradts, J

Iacocca, MV

Livasy, CA

Washburn, DB

Sayers, DE

Zhong, Z

Kiss, MZ

Thomlinson, WC

机构：

[1] Univ N Carolina, Sch Med, Dept Radiol, Chapel Hill, NC 27599 USA

[2] Univ N Carolina, Sch Med, Dept Pathol, Chapel Hill, NC 27599 USA

[3] Univ N Carolina, Sch Med, Lineberger Comprehens Canc Ctr, Chapel Hill, NC 27599 USA

[4] IIT, Dept Phys, Chicago, IL 60616 USA

[5] IIT, Ctr Synchrotron Radiat Res & Instrumentat, Chicago, IL 60616 USA

[6] Univ Oxford, Nuffield Dept Pathol & Bacteriol, Oxford OX1 2JD, England

[7] N Carolina State Univ, Dept Phys, Raleigh, NC 27695 USA

[8] Brookhaven Natl Lab, Upton, NY 11973 USA

[9] European Synchrotron Radiat Facil, F-38043 Grenoble, France

来源：

RADIOLOGY | 2000年 / 214卷 / 03期

关键词：

breast radiography; technology; synchrotron;

D O I：

10.1148/radiology.214.3.r00mr26895

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Seven breast cancer specimens were examined with diffraction-enhanced imaging at 18 keV with a silicon crystal with use of the silicon 333 reflection in Bragg mode. Images were compared with digital radiographs of the specimen, and regions of increased detail were identified. Six of the seven cases (86%) showed enhanced visibility of surface spiculation that correlated with histopathologic information, including extension of tumor into surrounding tissue.

引用

页码：895 / 901

页数：7

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