Isolation and structure of ciguatoxin-4A, a new ciguatoxin precursor, from cultures of dinoflagellate Gambierdiscus toxicus and parrotfish Scarus gibbus

被引：97

作者：

Satake, M

Ishibashi, Y

Legrand, AM

Yasumoto, T

机构：

[1] TOHOKU UNIV, FAC AGR,AOBA KU, SENDAI, MIYAGI 981, JAPAN

[2] INST TERR RECH MED LOUIS MALARDE, TAHITI, FRANCE

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1996年 / 60卷 / 12期

关键词：

ciguatera; ciguatoxin-4A (CTX4A); dinoflagellate; Gambierdiscus toxicus; scaritoxin;

D O I：

10.1271/bbb.60.2103

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A new ciguatoxin congener, ciguatoxin-4A (CTX4A), was isolated from cultures of marine dinoflagellate Gambierdiscus toxicus, and its structure was elucidated to be 52-epiciguatoxin-4B on the basis of spectroscopic data. Chromatographic and spectral comparisons indicated that CTX4A was identical with a structurally unelucidated congener known as scaritoxin or SG1.

引用

页码：2103 / 2105

页数：3

共 11 条

[1] STUDIES ON MARINE TOXINS .51. ISOLATION OF 2 TOXINS FROM A PARROT-FISH SCARUS-GIBBUS
CHUNGUE, E
BAGNIS, R
FUSETANI, N
HASHIMOTO, Y
[J]. TOXICON, 1977, 15 (01) : 89 - 93
[2] TOXIN COMPLEX FROM PARROT FISH
CHUNGUE, E
BAGNIS, R
FUSETANI, N
YASUMOTO, T
[J]. BIOCHIMIE, 1977, 59 (8-9) : 739 - 741
[3] Legrand A M, 1992, Bull Soc Pathol Exot, V85, P467
[4] LEGRAND AM, 1992, 3RD P INT C CIG FISH, P25
[5] STRUCTURE AND PARTIAL STEREOCHEMICAL ASSIGNMENTS FOR MAITOTOXIN, THE MOST TOXIC AND LARGEST NATURAL NON-BIOPOLYMER
MURATA, M
NAOKI, H
MATSUNAGA, S
SATAKE, M
YASUMOTO, T
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (16) : 7098 - 7107
[6] STRUCTURES AND CONFIGURATIONS OF CIGUATOXIN FROM THE MORAY EEL GYMNOTHORAX-JAVA']JAVANICUS AND ITS LIKELY PRECURSOR FROM THE DINOFLAGELLATE GAMBIERDISCUS-TOXICUS
MURATA, M
LEGRAND, AM
ISHIBASHI, Y
FUKUI, M
YASUMOTO, T
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (11) : 4380 - 4386
[7] THE STRUCTURE OF CTX3C, A CIGUATOXIN CONGENER ISOLATED FROM CULTURED GAMBIERDISCUS-TOXICUS
SATAKE, M
MURATA, M
YASUMOTO, T
[J]. TETRAHEDRON LETTERS, 1993, 34 (12) : 1975 - 1978
[8] GAMBIEROL - A NEW TOXIC POLYETHER COMPOUND ISOLATED FROM THE MARINE DINOFLAGELLATE GAMBIERDISCUS-TOXICUS
SATAKE, M
MURATA, M
YASUMOTO, T
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (01) : 361 - 362
[9] SATAKE M, 1993, DEV MAR BIO, V3, P575
[10] CIGUATOXIN - ISOLATION AND CHEMICAL NATURE
SCHEUER, PJ
TAKAHASHI, W
TSUTSUMI, J
YOSHIDA, T
[J]. SCIENCE, 1967, 155 (3767) : 1267 - +

← 1 2 →