Determination of endogenous gamma-hydroxybutyric acid (GHB) levels in antemortem urine and blood

被引:80
作者
Elian, AA [1 ]
机构
[1] Commonwealth Massachusetts, State Police Crime Lab, Forens Toxicol Unit, Sudbury, MA 01776 USA
关键词
gamma-hydroxybutyric acid; endogenous; antemortem GC-MS;
D O I
10.1016/S0379-0738(02)00183-4
中图分类号
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号
0301 ; 10 ;
摘要
Gamma-hydroxybutyric acid's (GHB's) natural presence in the body has made the interpretation of its levels a challenging task for the forensic toxicologist. This Study was designed to measure endogenous GHB levels in antemortem urine and blood samples. The range detected in urine was from 34 to 575 mug/dl and in blood from 17 to 151 mug/dl. The results indicate that the concentration of endogenous GHB in urine and blood concur with the suggested cut-off levels at 1000 and 500 mug/dl, respectively. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:120 / 122
页数:3
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