Mechanical properties of biocompatible protein polymer thin films

被引:32
作者
Buchko, CJ [1 ]
Slattery, MJ [1 ]
Kozloff, KM [1 ]
Martin, DC [1 ]
机构
[1] Univ Michigan, Macromol Sci & Engn Ctr, Dept Mat Sci & Engn, Ann Arbor, MI 48109 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1557/JMR.2000.0038
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
A silklike protein with fibronectin functionality (SLPF) (ProNectin F(R), Protein Polymer Technologies, Inc.) is a genetically engineered protein polymer containing structural and biofunctional segments. The mechanical properties and deformation mechanisms of electrostatically deposited SLPF thin films were examined by scratch testing, tensile testing, and nanoindentation, Scanning electron microscopy and scanned probe microscopy revealed that the macroscopic properties were a sensitive function of microstructure. The SLPF films were relatively brittle in tension, with typical elongation-to-break values of 3%. Nanoindentation data were fit to a power law relationship.
引用
收藏
页码:231 / 242
页数:12
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